NFAT1 transcription factor is central in the regulation of tissue...
AbstractMembers of the nuclear factor of activated T cell (NFAT) family of transcription factors were originally described in T lymphocytes but later shown to be expressed in several immune and...
View ArticlePlatelets: versatile effector cells in hemostasis, inflammation, and the...
AbstractPlatelets are chief effector cells in hemostasis. In addition, however, their specializations include activities and intercellular interactions that make them key effectors in inflammation and...
View ArticleIntegrin α D β 2 (CD11d/CD18) mediates experimental malaria-associated acute...
AbstractBackgroundMalaria-associated acute respiratory distress syndrome (MA-ARDS) is a potentially lethal complication of clinical malaria. Acute lung injury in MA-ARDS shares features with ARDS...
View ArticleHaem oxygenase protects against thrombocytopaenia and malaria-associated lung...
AbstractBackgroundMalaria-triggered lung injury can occur in both severe and non-severe cases. Platelets may interact with parasitized erythrocytes, leukocytes and endothelium. These interactions can...
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